I am a researcher in the field of computational biophysics.
Currently, my research interests are focused on the study of structural properties of biological macromolecules. My experience is mainly based on structural modeling and molecular dynamics simulations of these systems. More generally, I use different bioinformatic methods for understanding biological data.
Project I: structural validation of structural models of paracellular channels and design of novel molecules able to modulate the paracellular permeability.
Gene/Protein
CLDN5/Claudin 5
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Project II: understanding the molecular mechanisms of ion channels related to conductivity, selectivity and investigating the impact of disease associated variants.
Gene/Protein
SCN2A/Nav1.2
KCNQ2/Kv7.2
